The SOT Enhancement of Animal Welfare Award is presented annually to a member of the Society of Toxicology in recognition of contributions made to the advancement of toxicological science through the development and application of methods that replace, refine, or reduce the need for experimental animals. This award recognizes outstanding/significant contributions made by members of the Society of Toxicology to the scientifically sound and responsible use of animals in research. This award also serves to recognize member contributions to the public awareness of the importance of animals in toxicology research. The achievement recognized may be either a seminal piece of work or a long-term contribution to toxicological science and animal welfare. Items needed in the application are a letter of nomination from a full member of the Society; curriculum vitae of the nominee; and a seconding letter from a full member of the Society. Both nomination letters should provide documentation of specific methods used by the nominee to replace, refine, or reduce the need for experimental animals; and present analysis of significant contributions made by the nominee to scientifically sound and responsible use of animals in research. Preference will be given to nominees who have not received another SOT Award, defined as those conferred by the SOT Awards Committee, excluding Supported and Student awards, within the last two years. Please visit the award's website or contact the Society of Toxicology for more information.