The Leading Edge in Basic Science Award is presented to a scientist who, based on research, has made a recent (within the last five years), seminal scientific contribution/advance to understanding fundamental mechanisms of toxicity. The recipient should be a respected basic scientist whose research findings are likely to have a pervasive impact on the field of toxicology. Applicants may be a member or nonmember of the Society. Two letters of nomination from full members of the Society are required. Both letters should name the specific contribution(s) for which the scientist is nominated and discuss the potential impact on toxicology....