Discovery Boost Grants (DBG) are designed for exploratory research to develop methodologies, establish feasibility, or pilot test high risk/high reward projects across the cancer research continuum. The applicant's institution must provide space and other resources customary for independent investigators. Independent investigators at any career stage are eligible to apply. Investigators must have a doctorate degree, (MD, PhD, DVM, or equivalent), and have a full-time faculty position or equivalent at a college, university, medical school, or other fiscally responsible, not-for-profit research organization within the United States. There are no citizenship restrictions. Applicants must provide a list of collaborators, co-investigators, and consultants, then upload the letter from each individual collaborator, co-I, or consultant. The letter should outline the role that each person will play with sufficient detail for evaluation of the value of the individual contribution. The deadlines are April 1 and October 15. Please visit the award's website for more information and the complete application process.